Diagnosis and treatment of Carcinomatosis


Carcinomatosis is a type of cancer which leads to development of carcinomas in multiple forms and simultaneously from the primary source of the cancerous cells. Though similar to the other metastatic diseases, it is different in that it does not only involve the spread of the carcinomas from their sources to regional nodes because multiple sites will have multiple secondaries. There are many types of cancers whose carcinomas spread from source. Though some medical experts refer to all these forms as types of Carcinomatosis, the term should not include sarcomas or lymphomas and strictly speaking should only include carcinomas or epithelial cancers. Carcinomatosis is not easy to identify from the myriad of cancers and worse, treatment options are not completely curative but a control mechanism

How Carcinomatosis is diagnosed

The biggest challenge in the diagnosis of Carcinomatosis is that it presents itself with symptoms or diseases that are associated with other medical conditions. For example Carcinomatosis of the liver manifests as jaundice which can also result from other causes such as liver cirrhosis or gallstones. The latter diseases have to be tested for and ruled out before the jaundice is ruled out to be specifically as a result of Carcinomatosis. Of course there are other properties of cancerous cells that will be used to tell if the disease is as a result of Carcinomatosis or not.

When the presence of carcinomas or cancerous cells can be identified with in a n organ to gether with the following diseases, then it is a strong indication of Carcinomatosis:

·         Haemoptysis in the lungs

·         Neurological diseases of the brain

·         Pathological fracture of bones

When Carcinomatosis is the biggest suspect, the doctors will seek to find a primary tumor which, to complicate the diagnosis process, may lack in up to six percent of the patients. Recent improvement in investigative technology is providing the much needed breakthrough for the process with histology being the leading breakthrough so far though it can be anaplastic and result in no convincing diagnosis at all.

How Carcinomatosis is managed

Aforementioned, there is no realistic means of curing Carcinomatosis. Available common treatments for several types of cancers, like chemotherapy and radiotherapy produce a minimal effect, often palliative. Surgery is often performed on the carcinomas. Such surgery debaulks the tumour so that chemotherapy thoroughly destroys the infected epithelial tissues. For the liver cases, the metastases that are secondary to colorectal cancer may be resectioned leading to limited number of successes in different patients.

On the flip side there are patients who have had considerable success with the mainstream chemotherapy and radiotherapy in combination to other treatment forms. For example, patients who have leptomeningeal metastases that are a secondary of cancer of the breast have been to improve to the point of recovery with a combination of intravenous chemotherapy, intrathecal chemotherapy, radiotherapy applied to spinal leptomeninges and radiotherapy for the whole brain. For the patients who have no hope of imptovement pain control and dyspnoea in palliative care or dying at home management techniques can still be used.


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